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Dendritic cells loaded with tumor derived exosomes for cancer immunotherapy  期刊论文   WOS高被引论文 WOS热点论文

  • 编号:
    F76B9475FC7477314085D971610C0072
  • 作者:
    Liu, Hongyu#[1]Chen, Ling#[1]Peng, Yaojun[2];Yu, Songyan[3];Liu, Jialin[1];Wu, Liangliang[2];Zhang, Lijun[2];Wu, Qiyan[2];Chang, Xin(常鑫)[4]Yu, Xinguang*[1]Liu, Tianyi*[2]
  • 语种:
    英文
  • 期刊:
    ONCOTARGET ISSN:1949-2553 2018 年 9 卷 2 期 (2887 - 2894) ; JAN 5
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  • 摘要:

    Exosomes are vesicles that can be secreted by many types of cell and released into the extracellular space. Studies have found that tumor derived exosomes (TEXs) can promote tumor growth and metastasis, as well as inhibit immune response through transferring their genetic information to the recipient cells. Given their functions in tumor progression, TEXs are considered as promising biomarkers for early detection of human malignancy. Dendritic cells (DCs), a type of antigen presenting cells, can induce tumor-specific T cell immune responses in carcinogenesis. Growing evidences have demonstrated that the matured DCs induced by TEXs exhibit enhanced anti-tumor effects that may be applied for cancer immunotherapy. Thus in this review, according to the previous studies, we summarized the effects of DCs loaded with TEXs in cancer immunotherapy.

  • 推荐引用方式
    GB/T 7714:
    Liu Hongyu,Chen Ling,Peng Yaojun, et al. Dendritic cells loaded with tumor derived exosomes for cancer immunotherapy [J].ONCOTARGET,2018,9(2):2887-2894.
  • APA:
    Liu Hongyu,Chen Ling,Peng Yaojun,Yu Songyan,&Liu Tianyi.(2018).Dendritic cells loaded with tumor derived exosomes for cancer immunotherapy .ONCOTARGET,9(2):2887-2894.
  • MLA:
    Liu Hongyu, et al. "Dendritic cells loaded with tumor derived exosomes for cancer immunotherapy" .ONCOTARGET 9,2(2018):2887-2894.
  • 入库时间:
    7/17/2020 8:51:49 AM
  • 更新时间:
    7/17/2020 8:51:49 AM
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